Audiences first caught a glimpse of Madsen as Princess Irulan in David Lynch's science fiction epic Dune (1984). Madsen first became popular with audiences in 1986 with her portrayal of a Catholic school girl who fell in love with a boy from a prison camp in Duncan Gibbons' Fire with Fire. Madsen's other noted film appearances include 1990's The Hot Spot with Don Johnson, and the steamy Third Degree Burn with Treat Williams. In 2004 she had a comeback of sorts with Sideways, which garnered her rave reviews and Academy Award and Golden Globe nominations.
Madsen's older brother Michael Madsen is also an actor (he refuses to see any films in which she has a nude scene), and her mother Elaine Madsen is an Emmy-winning writer and producer. When Madsen arrived in Hollywood she was engaged to actor Billy Campbell. She was married to Danny Huston from 1989 to 1992. She later had a relationship with actor Antonio Sabato Jr., which in 1994 produced a son, Zack.
--Wikipedia
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