Born and raised in Pasadena, California, Bush started her career on her high school theater stage. Having been crowned the Pasadena Rose Queen, Bush quickly attracted representation.

Soon after Bush landed her first film role, in the comedy Van Wilder with Ryan Reynolds and Tara Reid. Bush played Sally, a freshman in college who harbored a huge crush on Reynolds' character. She also appeared in HBO's Point of Origin with Ray Liotta and John Leguizamo and the independent film Learning Curves.

Recently, Bush was featured in a three-episode arc in the drama Nip/Tuck as a devious teenage bisexual. She also made a guest appearance on The WB's Sabrina The Teenage Witch as Sabrina's archrival.

Currently living in Wilmington, North Carolina while filming the series, Bush is an avid scrap-booker. Besides taking photographs for her books, she enjoys reading and spending time with her friends.