Sofia Milos starred in the television series The Secret Lives of Men and Caf頁mericain. She has also appeared in The Sopranos, Curb Your Enthusiasm, Caroline in the City, Friends, Mad About You and Thieves.

Milos began modeling when she was 15 to help pay her way through business school in Switzerland. However, in 1990, she moved to the United States to pursue an acting career. Following several television roles, she appeared in the feature films Screw Loose, Jane Austen's Mafia! The Ladies Man and Dalia, and Passionada. She is also an avid painter.

Milos was born in Zurich and raised in Rome. She has also lived in Los Angeles.