Jessica Collins was born in San Antonio, Texas. After attending high school at Tom C. Clark High, she pursued her passion and gift for acting at the famous Juilliard School in New York. There she performed in such classic productions as "Macbeth," "Three Sisters" and "Faust."

During her Juilliard training, she was also hand selected to attend an acting program at the British American Drama Academy in Oxford, England. Upon graduation in 2005, she made her television debut playing twins on the series "The Ghost Whisperer," then guest-starred on "Law & Order: Criminal Intent." Soon after that, she made her off-Broadway debut in the world premiere of "Manic Flight Reaction" at Playwrights Horizons.