Jennifer Tilly received both an Academy Award Nomination, and an American Comedy award nomination for her role as Olive in Woody Allen's Bullets over Broadway.

Her performance as Jim Carrey's gold digging client in Liar, Liar earned her another American Comedy Award nomination, as well as a Blockbuster award nomination as Favorite Supporting Actress.

Tilly's other film credits include Bound (Saturn award nominee-Best Actress, GLAAD award recipient), The Muse, Relax, it's Just Sex, Stuart Little, The Getaway, Made in America, Bride of Chucky (Saturn award nominee-Best Actress), Shadow of the Wolf, Let it Ride, The Crew and The Fabulous Baker Boys.

On television, Tilly starred in the miniseries Bella Mafia with Vanessa Redgrave, and in the Fox series Key West. She also starred with Diane Keaton in director Marshall Brickman's Sister Mary Explains it All for Showtime, and in a remake of The Magnificent Ambersons directed by Alphonso Arau (Like Water For Chocolate) for A&E Networks. Tilly received a CableAce award nomination (Best Actress in a Comedy) for her recurring role as Garry's girlfriend, Angelica, on The Garry Shandling Show. For her role in the Showtime movie Heads, she received a Gemini award nomination for Best Actress. Tilly also appeared as Crystal in CBS's Out of Practice.

Tilly's extensive stage credits include Tartuffe and Boy's Life at the LATC, as well as Baby with the Bathwater and The Woolgatherer at the LA Public Theatre. She received a Dramalogue Award for her work in Vanities, and a TheatreWorld award for Outstanding Newcomer for her performance in One Shoe Off at the Joseph Papp Theatre.

Tilly also completed Fast Sofa with Crispin Glover and Natasha Lyonne.