Swain found stardom playing the title role in the most recent film version of Lolita directed by Adrian Lyne. She was chosen out of thousands of submissions during a nationwide search to cast the title role opposite Jeremy Irons. She will be seen next opposite Christina Ricci in the Zoetrope Productions/MGM feature, Pumpkins.

Shortly thereafter, Swain will be seen in two independent features: Dead in the Water opposite Henry Thomas and Scott Bairstow and Briar Patch, again opposite Henry Thomas. Most recently she has been seen in the title role of the independent film, Intern, opposite Kathy Griffen and Ben Pullen. Swain has also completed filming the starring role in New Line Cinema's Happy Campers, and an independent feature, Tart.

Other film credits include Face/Off for director John Woo and Girl directed by Jonathan Kahn.